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Causes of HyperhidrosisWhile doctors don't know why hyperhidrosis starts, the most likely cause is a genetic one. They have successfully linked it to over activity in the sympathetic nervous system. Specifically, it is the Thoracic Sympathetic Ganglion Chain, which runs along the vertebra of the spine inside the chest cavity.
This chain controls the glands, known as the apocrine and eccrine glands, responsible for perspiration throughout the entire body. The eccrine sweat glands are mainly concentrated in the palms of the hands and soles of the feet. In most cases the hands and feet are effected. To a lesser degree, the face and armpit (axillae) regions are effected. Another manifestation of the hyperactive sympathetic activity is facial blushing. Sometimes people perspire heavily because of other illnesses such as hyperthyroidism, psychiatric disorders, menopause and obesity. These causes must first be ruled out before Primary Hyperhidrosis can be diagnosed.
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